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| The time of administration of medicine is called as ‘Aushadha sevana kala’. The efficacy and safety of medicine vary as per the time of administration. Chrono-pharmacology deals with studies of biological rhythm dependencies of drugs regarding its pharmacological effects and/or pharmacokinetics/dynamics of drugs in both animals and humans. | | The time of administration of medicine is called as ‘Aushadha sevana kala’. The efficacy and safety of medicine vary as per the time of administration. Chrono-pharmacology deals with studies of biological rhythm dependencies of drugs regarding its pharmacological effects and/or pharmacokinetics/dynamics of drugs in both animals and humans. |
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| In Ayurveda, different times of medicine administration are mentioned for pacification (shamana) therapies. [A. Hr. Sutra Sthana 13]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The principle of circadian rhythm of [[dosha]], their influence on human physiology is considered to achieve highest active potential of a medicine. By applying this principle of chrono-pharmacology, maximum efficacy can be achieved even in smaller doses. Moreover, a single medicine can be used in different disorders as per biological rhythms and states of [[dosha]]. Thus, the requirement of medicine can be reduced to treat multiple disorders. Duration of medical treatment in chronic disorders can also be reduced. | | In Ayurveda, different times of medicine administration are mentioned for pacification (shamana) therapies. [A. Hr. Sutra Sthana 13]<ref name= Hridaya > Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.</ref> The principle of circadian rhythm of [[dosha]], their influence on human physiology is considered to achieve highest active potential of a medicine. By applying this principle of chrono-pharmacology, maximum efficacy can be achieved even in smaller doses. Moreover, a single medicine can be used in different disorders as per biological rhythms and states of [[dosha]]. Thus, the requirement of medicine can be reduced to treat multiple disorders. Duration of medical treatment in chronic disorders can also be reduced. |
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| This article describes the time of administration of medicine and its application in clinical practice. | | This article describes the time of administration of medicine and its application in clinical practice. |
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| {{Infobox | | {{Infobox |
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| |label5 = Correspondence email: | | |label5 = Correspondence email: |
− | |data5 = carakasamhita@gmail.com | + | |data5 = draneesheg@gmail.com, |
| + | dryogeshdeole@gmail.com, |
| + | carakasamhita@gmail.com |
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| |label6 = Date of publication | | |label6 = Date of publication |
| |data6 = May 21, 2021 | | |data6 = May 21, 2021 |
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| |label7 = DOI | | |label7 = DOI |
− | |data7 = Awaited | + | |data7 = 10.47468/CSNE.2021.e01.s09.056 |
| }} | | }} |
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| ==Synonyms== | | ==Synonyms== |
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| ==More information== | | ==More information== |
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− | [[Yonivyapat Chikitsa]] | + | [[Yonivyapat Chikitsa]] [[Chikitsa Sthana]] |
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| ==Abbreviations== | | ==Abbreviations== |
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| Cha. = Charak, Su. = Sushruta, A. = Ashtanga, S. = Sangraha, Hr. = Hridaya, Sa. = Samhita, Ka. = Kasyapa, Sha. = Sharangadhara | | Cha. = Charak, Su. = Sushruta, A. = Ashtanga, S. = Sangraha, Hr. = Hridaya, Sa. = Samhita, Ka. = Kasyapa, Sha. = Sharangadhara |
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| + | <big>'''[[Special:ContactMe|Send us your suggestions and feedback on this page.]]'''</big> |
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| ==References== | | ==References== |
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| </div> | | </div> |
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