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<li>Hrasiyasi matra (minimum dose): This dose of aushadha is smaller than the hriswa or laghu matra and thus gets digested before 6 hours. This dose is used as a test dose when the strength of the digestive system in unknown.<ref>Tripathi R.D., (1 st ed.). Commentary Saroj on Astanga Sangrah of Vridhavagabhata, Sutra Sthana; Snehavidhi Adhyaya: Chapter 25, Verse 23. Delhi: Chaukhamba Sanskrit Pratishthan, 2015; 452.</ref></li></ul></ul>
<li>Hrasiyasi matra (minimum dose): This dose of aushadha is smaller than the hriswa or laghu matra and thus gets digested before 6 hours. This dose is used as a test dose when the strength of the digestive system in unknown.<ref>Tripathi R.D., (1 st ed.). Commentary Saroj on Astanga Sangrah of Vridhavagabhata, Sutra Sthana; Snehavidhi Adhyaya: Chapter 25, Verse 23. Delhi: Chaukhamba Sanskrit Pratishthan, 2015; 452.</ref></li></ul></ul>
There is no specific common matra of aushadhi for everyone. The matra of aushadha of individual depends on time (kala), digestive capacity (agni), age (vaya), strength (bala), body constitution (prakriti), dosha and habitat (desha).<ref>Sharangdhar purvakhand 1/37 Tripathi B, editor, (1st ed.). Commentary Dipika on Sharangadhar Samhita of Sharangadhar, Purva Khanda; Adhyaya: Chapter 1, Verse 37. Varanasi: Chaukhamba Surbharti Prakashan, 2011; 10.</ref> [Cha. Sa. Kalpa Sthana 12/86].
There is no specific common matra of aushadhi for everyone. The matra of aushadha of individual depends on time (kala), digestive capacity (agni), age (vaya), strength (bala), body constitution (prakriti), dosha and habitat (desha).<ref>Sharangdhar purvakhand 1/37 Tripathi B, editor, (1st ed.). Commentary Dipika on Sharangadhar Samhita of Sharangadhar, Purva Khanda; Adhyaya: Chapter 1, Verse 37. Varanasi: Chaukhamba Surbharti Prakashan, 2011; 10.</ref> [Cha. Sa. Kalpa Sthana 12/86].
=== Time of consumption of aushadha ===
<div style='text-align:justify;'>The pharmacokinetics of aushadha is dependent on the biological rhythm of the body. Thus, to obtain maximum health benefits, aushadha must be administered at proper time depending on the patient's disease, strength, and age. Bheshaj kala (or aushadha sevana kala or aushadha apeksha kala) is the proper time for administration of aushadha. Ashtang Sangraha mentioned eleven<ref>Tripathi R.D., (1 st ed.). Commentary Saroj on Astanga Sangrah of Vridhavagabhata, Sutra Sthana; Bheshajavacharaniya Adhyaya: Chapter 23, Verse 12. Delhi: Chaukhamba Sanskrit Pratishthan, 2015; 428.</ref>; Charak [Cha. Sa. Chikitsa Sthana 30/298], Sushruta<ref>Shastri A D, editor, (1st ed.). Commentary Ayurveda Tattva Sandipika of Ambikadutta Shastri on Sushruta Samhita, Uttar Tantra; Swasthavrittam Adhyaya: Chapter 64, Verse 67. Varanasi: Chaukhamba Sanskrit Sansthan, 2016; 624.</ref> [Su. Sa. Uttara Tantra 64/67], Ashtangh Hridaya<ref>Murthy K.R.S., editor, (8th ed.). Vagbhata’s Ashtanga Hridayam, Sutra Sthana; Doshopakramaniya Adhyaya: Chapter 13, Verse 37. Varanasi: Chowkhamba Krishnadas Academy, 2011; 190.</ref> [A. Hri. Sutra Sthana 13/37] and Kashyap<ref>Satyapala, editor, (1st ed.). Commentary Vidyotini of Kashyap Samhita, Khila Sthana; Bheshajyopakramaniya Adhyaya: Chapter 3, Verse 52. Varanasi: Chaukhamba Sanskrit Sansthan, 2015; 369.</ref> mentioned ten aushadha sevan kala. Sharangadhara<ref>Tripathi B, editor, (1st ed.). Commentary Dipika on Sharangadhar Samhita of Pandita Sharangadharacharya, Purva Khanda; Bhaishajyakhyan: Chapter 2, Verse 2-3. Varanasi: Chaukhamba Surbharti Prakashan, 2011; 24.</ref> mentioned five suitable periods of administration of aushadha (aushadha kala). The aushadha kala are as below: [Cha. Sa. Chikitsa Sthana 30/298]
<ol><li>A strong patient must consume aushadha empty stomach in the morning</li>
<li>A weak patient must consume aushadha mixed with light and digestible wholesome food</li>
<li>Bhukta-adau: before the meals.</li>
<li>Bhukta-madhye: during the meal or in the middle of the meal.</li>
<li>Bhukta-pashchat: after the meal.</li>
<li>Muhurmuhu: Frequently during the day and night.</li>
<li>Samudga: between two meals.</li>
<li>Bhakta-samyujta: mixed with the food.</li>
<li>Grase: along with each morsel of food.</li>
<li>Grasantare: between two morsels of food.</li>
</ol></div>
=== Mode of action of aushadha ===
<div style='text-align:justify;'>The action of the aushadha depends upon its potency.<ref>Shastri A D, editor, (1st ed.). Commentary Ayurveda Tattva Sandipika of Ambikadutta Shastri on Sushruta Samhita, Sutra Sthana; Dravyarasagunaviryavipakavigyaniya Adhyaya: Chapter 40, Verse 5. Varanasi: Chaukhamba Sanskrit Sansthan, 2015; 195.</ref> [Su. Sa. Sutra Sthana 40/5] Some scholars believed the potency to be of two types (hot and cold) while others believed it to be of eight types (cold, hot, oily, dry, clear, slimy, mild and sharp). For example, mahatpanchamula (combination of roots of Aegle marmelos, Clerodendrum phlomidis, Oroxylum indicum, Stereospermum suaveolens and Gmelina arborea) alleviate vata dosha due to their hot potency (since vata dosha is cold in property). Kulattha (Dolichos biflorus) and onion (Allium cepa) alleviate vata due to oily character (since vata is dry in property). Cane sugar (Saccharum officinarum) increases vata due to its cold potency. </div>
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