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The method of use, quantity, time of application and other pharmacotherapeutic aspects are not in scope of this chapter. However, it is to be noted that an ''alepa'' is generally advised for application against the direction of the hair growth (pratiloma) to enhance its penetration (''swedavahi shira'') 23.
 
The method of use, quantity, time of application and other pharmacotherapeutic aspects are not in scope of this chapter. However, it is to be noted that an ''alepa'' is generally advised for application against the direction of the hair growth (pratiloma) to enhance its penetration (''swedavahi shira'') 23.
 
==== Measurement ====  
 
==== Measurement ====  
The quantity, or dosage, of medication in the case of topical medicines is measured by the thickness of the layer of paste. Typically, it should be equivalent to the thickness of fresh skin of a buffalo 24. Thickness of a layer of ''pralepa'' should be equivalent to the thickness of a typical chandana (sandal paste) application. Pradeha is typically applied as a thick paste or bolus (pinda)25. Thus, it is thin and thick pastes for application of pralepa/anulepana and pradeha respectively 26,27.
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The quantity, or dosage, of medication in the case of topical medicines is measured by the thickness of the layer of paste. Typically, it should be equivalent to the thickness of fresh skin of a buffalo 24. Thickness of a layer of ''pralepa'' should be equivalent to the thickness of a typical ''chandana'' (sandal paste) application. ''Pradeha'' is typically applied as a thick paste or bolus (''pinda'')25. Thus, it is thin and thick pastes for application of ''pralepa/anulepana'' and ''pradeha'' respectively 26,27.
    
==== Indication and contraindications ====
 
==== Indication and contraindications ====