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Transient nervous system collapse of a person which leads to various signs and symptoms enlisted in the verses 7 to 13. The cluster describes features of paroxysmal stage of ''apasmara''. The features include somatic as well as psychological subjective symptoms experienced by patients self. The dreams specific to predominance of ''dosha'' can be important measures for diagnosis of predominance of ''dosha''. The symptomatology has been described elaborately in context of [[Apasmara Nidana]].
 
Transient nervous system collapse of a person which leads to various signs and symptoms enlisted in the verses 7 to 13. The cluster describes features of paroxysmal stage of ''apasmara''. The features include somatic as well as psychological subjective symptoms experienced by patients self. The dreams specific to predominance of ''dosha'' can be important measures for diagnosis of predominance of ''dosha''. The symptomatology has been described elaborately in context of [[Apasmara Nidana]].
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==== Gut-brain connection in apasmara ====
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==== Gut-brain connection in ''apasmara'' ====
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Gut-brain dysfunction is proved to play role in many psychiatric disorders like depression, anxiety, autism, schizophrenia. The figure shows physiology of gut-brain connection [fig. ]. As discussed earlier in Apasmara Nidana chapter 8, many of the somatic symptoms are related with the dysfunction of gastro-intestinal tract.Therefore the possibility of gut-brain dysfunction can’t be denied. Similarly, as seen above, many of the animal products like medicines formulated with cow’s urine, cow’s ghee, goat urine that are rich in micro-organisms are enlisted in management of apasmara. The exact pharmaco-dynamic behind action of these medicines in management of apasmara with focus on gut-brain axis needs to be investigated.  
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Gut-brain dysfunction is proved to play role in many psychiatric disorders like depression, anxiety, autism, schizophrenia. The figure shows physiology of gut-brain connection [fig. ]. As discussed earlier in [[Apasmara Nidana]], many of the somatic symptoms are related with the dysfunction of gastrointestinal tract.Therefore the possibility of gut-brain dysfunction cannot be denied.  
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Similarly, as seen above, many of the animal products like medicines formulated with cow’s urine, cow’s ghee, goat urine that are rich in micro-organisms are enlisted in management of ''apasmara''. The exact pharmaco-dynamic behind action of these medicines in management of ''apasmara'' with focus on gut-brain axis needs to be investigated.
    
==== Etio-Pathogenesis of Atattvabhinivesha ====
 
==== Etio-Pathogenesis of Atattvabhinivesha ====