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Metabolic process and thermoregulatory center situated in hypothalamus play key role to generate and maintain body temperature respectively. Reduced temperature shows slow metabolic process and gradually it ceases completely, causing death.  
 
Metabolic process and thermoregulatory center situated in hypothalamus play key role to generate and maintain body temperature respectively. Reduced temperature shows slow metabolic process and gradually it ceases completely, causing death.  
With the help of healthy digestive power and proper metabolic activity; food nourishes the body and provide macro and micronutrients to the body.<ref>Acharya JT, editor. Charak Samhita of Agnivesha, Chikitsasthana 4th ed. Ch. 15, Ver. 3. Varanasi: Chaukhambha Surabharati Prakashana; 1994. p. 512  </ref>
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With the help of healthy digestive power and proper metabolic activity; food nourishes the body and provide macro and micronutrients to the body.[[[Charak Samhita]] [[Chikitsa Sthana]] 15/3]
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In any manner, hampered blood or oxygen supply to the brain leads to lack of concentration, weakness of mental functions or agitation. Deposition of any toxic substance or progressive degenerative changes of mind also leads to such symptoms. Ageing and death are considered as natural process with passage of time.<ref>Acharya JT, editor. Charak Samhita of Agnivesha, Sharirasthana 4th ed. Ch. 4, Ver. 36. Varanasi: Chaukhambha Surabharati Prakashana; 1994. p. 323 </ref> With declining phase of life, ageing symptoms start to appear, as new cell production is almost stops and older cell destruction continues. With the passage of senescence; weakness, decreasing appetite, muscular wasting, decreased fluid intake, neurological dysfunctions, decreasing level of consciousness etc. are common symptoms manifest and gradually leads to cessation of life.<ref>httpendlink.lurie.northwestern.edulast_hours_of_livingpart_one.pdf  </ref>
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In any manner, hampered blood or oxygen supply to the brain leads to lack of concentration, weakness of mental functions or agitation. Deposition of any toxic substance or progressive degenerative changes of mind also leads to such symptoms. Ageing and death are considered as natural process with passage of time.[[[Charak Samhita]] [[Sharira Sthana]] 4/36] With declining phase of life, ageing symptoms start to appear, as new cell production is almost stops and older cell destruction continues. With the passage of senescence; weakness, decreasing appetite, muscular wasting, decreased fluid intake, neurological dysfunctions, decreasing level of consciousness etc. are common symptoms manifest and gradually leads to cessation of life.  
    
Every individual has good appetite and capability of digesting foods he regularly ingests. ''Ksheerada''(only on milk), ''ksheera-anna''(milk and rice products), ''annada'' (staple foods), are three basic stages of life. During ageing process, gradual reduction in both qualitative consumption and digestive abilities are observed. This in turn influences the individual’s physical and mental wellbeing leading to reduction in life span ending in death.[3]
 
Every individual has good appetite and capability of digesting foods he regularly ingests. ''Ksheerada''(only on milk), ''ksheera-anna''(milk and rice products), ''annada'' (staple foods), are three basic stages of life. During ageing process, gradual reduction in both qualitative consumption and digestive abilities are observed. This in turn influences the individual’s physical and mental wellbeing leading to reduction in life span ending in death.[3]
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Gradual cessation of the functions is a clear indication of either degenerative changes or space occupying lesion (SOL) in the specific area. Acute toxicity of brain also leads to acute degeneration of brain cells or infarction that leads to hampering of function. [7]
 
Gradual cessation of the functions is a clear indication of either degenerative changes or space occupying lesion (SOL) in the specific area. Acute toxicity of brain also leads to acute degeneration of brain cells or infarction that leads to hampering of function. [7]
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Sudden appearance of crescent shaped streaks or blood vessel network on forehead may relate with Amyloidosis. It is a rare disease that occurs when a protein (albumoid) substance gets deposited in person’s organ. This abnormal protein is usually produced in bone marrow and can be deposited in any tissue or organ. The prognosis is poor. [8-9]<ref>the description is based on https://en.wikipedia.org/wiki/Amyloidosis, accessed on 15/10/2015 </ref>   
 
Sudden appearance of crescent shaped streaks or blood vessel network on forehead may relate with Amyloidosis. It is a rare disease that occurs when a protein (albumoid) substance gets deposited in person’s organ. This abnormal protein is usually produced in bone marrow and can be deposited in any tissue or organ. The prognosis is poor. [8-9]<ref>the description is based on https://en.wikipedia.org/wiki/Amyloidosis, accessed on 15/10/2015 </ref>