| In a study on 36 cancer patients, effect of a polyherbal rasayana formulation was studied as an adjuvant to radiotherapy and chemotherapy. The rasayana preparation was made from Emblica officinalis (amalaki), Withania somnifera (ashwagandha), Tinospora cordifolia (guduchi), Glycirrhiza glabra (yashtimadhu), Leptadenia reticulata (jivanti), Ocimum sanctum (tulasi) and Piper longum (pippali), in electuary form. It effectively reduces the symptoms like vomiting, mucocitis, fatigue, xerostomia, alopecia, and tastelessness than those treated without rasayana. The weight loss associated with the cancer treatment was comparatively less in patients treated with rasayana compound. Flavonoids present in these herbs, are potent anti oxidant and provide protection against H2O2 cytotoxicity, created by radiotherapy. It also helps in the termination of lipid peroxidation chain reaction which is formed as a result of chemotherapeutic cytotoxic agents.<ref name=vyasp>Vyas P, Thakar AB, Baghel MS, Sisodia A, Deole Y. Efficacy of Rasayana Avaleha as adjuvant to radiotherapy and chemotherapy in reducing adverse effects. Ayu. 2010 Oct;31(4):417-23. doi: 10.4103/0974-8520.82029. PMID: 22048532; PMCID: PMC3202271.</ref> | | In a study on 36 cancer patients, effect of a polyherbal rasayana formulation was studied as an adjuvant to radiotherapy and chemotherapy. The rasayana preparation was made from Emblica officinalis (amalaki), Withania somnifera (ashwagandha), Tinospora cordifolia (guduchi), Glycirrhiza glabra (yashtimadhu), Leptadenia reticulata (jivanti), Ocimum sanctum (tulasi) and Piper longum (pippali), in electuary form. It effectively reduces the symptoms like vomiting, mucocitis, fatigue, xerostomia, alopecia, and tastelessness than those treated without rasayana. The weight loss associated with the cancer treatment was comparatively less in patients treated with rasayana compound. Flavonoids present in these herbs, are potent anti oxidant and provide protection against H2O2 cytotoxicity, created by radiotherapy. It also helps in the termination of lipid peroxidation chain reaction which is formed as a result of chemotherapeutic cytotoxic agents.<ref name=vyasp>Vyas P, Thakar AB, Baghel MS, Sisodia A, Deole Y. Efficacy of Rasayana Avaleha as adjuvant to radiotherapy and chemotherapy in reducing adverse effects. Ayu. 2010 Oct;31(4):417-23. doi: 10.4103/0974-8520.82029. PMID: 22048532; PMCID: PMC3202271.</ref> |
− | Administration of tuvaraka rasayana (rasayana preparation made out of Hydnocarpus laurifolia) alternatively for 5 days in a patient with psoriasis vulgaris showed reduction in PASI score from 42 to 3.8. The rasayana was administered after purification procedures. Complete remission of the lesions making PASI score 0 was observed. The histopathological study also reveals the complete remission of psoriasis on follow-up.<ref name=krishnakumar>Krishna Kumar K, Chacko J. Thuvaraka rasayana regimen in Psoriasis vulgaris - A case report. J Ayurveda Integr Med. 2019 Jan-Mar;10(1):41-44. doi: 10.1016/j.jaim.2018.04.003. Epub 2019 Jan 1. PMID: 30606464; PMCID: PMC6470303.</ref> | + | Administration of tuvaraka rasayana (rasayana preparation made out of Hydnocarpus laurifolia) alternatively for 5 days in a patient with psoriasis vulgaris showed reduction in PASI score from 42 to 3.8. The rasayana was administered after purification procedures. Complete remission of the lesions making PASI score 0 was observed. The histopathological study also reveals the complete remission of psoriasis on follow-up.<ref name=krishnakumar>Krishna Kumar K, Chacko J. Thuvaraka rasayana regimen in Psoriasis vulgaris - A case report. J Ayurveda Integr Med. 2019 Jan-Mar;10(1):41-44. doi: 10.1016/j.jaim.2018.04.003. Epub 2019 Jan 1. PMID: 30606464; PMCID: PMC6470303.</ref> |