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With the due course of time the disease (''kamala'') becomes deep seated (''kharibhuta'') resulting in excessive dryness of the body or afflicted tissue and thus becomes difficult to cure. This condition is called ''kumbha kamala'' [36½]
 
With the due course of time the disease (''kamala'') becomes deep seated (''kharibhuta'') resulting in excessive dryness of the body or afflicted tissue and thus becomes difficult to cure. This condition is called ''kumbha kamala'' [36½]
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==== Bad prognostic symptoms of kāmalā ====
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==== Bad prognostic symptoms of ''kamala'' ====
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कृष्णपीतशकृन्मूत्रो [१] भृशं शूनश्च मानवः||३७||  
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कृष्णपीतशकृन्मूत्रो [१] भृशं शूनश्च मानवः||३७||
 +
 
सरक्ताक्षिमुखच्छर्दिविण्मूत्रो यश्च ताम्यति|  
 
सरक्ताक्षिमुखच्छर्दिविण्मूत्रो यश्च ताम्यति|  
 
दाहारुचितृषानाहतन्द्रामोहसमन्वितः||३८||  
 
दाहारुचितृषानाहतन्द्रामोहसमन्वितः||३८||  
 +
 
नष्टाग्निसञ्ज्ञः क्षिप्रं हि कामलावान् विपद्यते|38½|  
 
नष्टाग्निसञ्ज्ञः क्षिप्रं हि कामलावान् विपद्यते|38½|  
 +
 
kr̥ṣṇapītaśakr̥nmūtrō [1] bhr̥śaṁ śūnaśca mānavaḥ||37||  
 
kr̥ṣṇapītaśakr̥nmūtrō [1] bhr̥śaṁ śūnaśca mānavaḥ||37||  
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saraktākṣimukhacchardiviṇmūtrō yaśca tāmyati|  
 
saraktākṣimukhacchardiviṇmūtrō yaśca tāmyati|  
 
dāhārucitr̥ṣānāhatandrāmōhasamanvitaḥ||38||  
 
dāhārucitr̥ṣānāhatandrāmōhasamanvitaḥ||38||  
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naṣṭāgnisañjñaḥ kṣipraṁ hi kāmalāvān vipadyatē|38½|
 
naṣṭāgnisañjñaḥ kṣipraṁ hi kāmalāvān vipadyatē|38½|
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kRuShNapItashakRunmUtro [1] bhRushaM shUnashca mAnavaH||37||  
 
kRuShNapItashakRunmUtro [1] bhRushaM shUnashca mAnavaH||37||  
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saraktAkShimukhacchardiviNmUtro yashca tAmyati|  
 
saraktAkShimukhacchardiviNmUtro yashca tAmyati|  
 
dAhArucitRuShAnAhatandrAmohasamanvitaH||38||  
 
dAhArucitRuShAnAhatandrAmohasamanvitaH||38||  
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naShTAgnisa~jj~jaH kShipraM hi kAmalAvAn vipadyate|38½|  
 
naShTAgnisa~jj~jaH kShipraM hi kAmalAvAn vipadyate|38½|  
If the stool and urine of the patient (of kāmalā) become black and yellow; develops excessive edema; eyes and face becomes red coloured; vomit, stool and urine are mixed with blood; the patient feels like going in darkness; has burning sensation, anorexia, morbid thirst, constipation, drowsiness and fainting; and the person looses his agni and consciousness; such patient may succumb to death quickly (37-38½).
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If the stool and urine of the patient (of ''kamala'') become black and yellow; develops excessive edema; eyes and face becomes red colored; vomit, stool and urine are mixed with blood; the patient feels like going in darkness; has burning sensation, anorexia, morbid thirst, constipation, drowsiness and fainting; and the person looses his ''agni'' and consciousness; such patient may succumb to death quickly [37-38½]
    
==== Principles of treatment ====
 
==== Principles of treatment ====