Dhatu: Difference between revisions

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National  Seminar  on ‘Rasayana’  opened The New  Indian  Express,  News  
National  Seminar  on ‘Rasayana’  opened The New  Indian  Express,  News  
article  published  on  Monday,  June  11,  2012
article  published  on  Monday,  June  11,  2012
Dhatu and body tissues:  
Dhatu and body tissues:  
In current perspective of human physiology, the seven dhatu correspond to seven kinds of basic tissues as below:  
In current perspective of human physiology, the seven dhatu correspond to seven kinds of basic tissues as below:  
Rasa: plasma including interstitial fluid and lymph  
Rasa: plasma including interstitial fluid and lymph  
Rakta: elements of blood and electrolytes  
Rakta: elements of blood and electrolytes  
Mamsa: muscle tissue  
Mamsa: muscle tissue  
Meda: adipose tissue  
Meda: adipose tissue  
Asthi: bone tissue  
Asthi: bone tissue  
Shukra: elements of reproductive tissues  
Shukra: elements of reproductive tissues  
Dhatvagni and tissue metabolism:  
 
The tissue metabolism corresponds to functions of dhatvagni at various levels as below:
'''Dhatvagni and tissue metabolism:'''
 
The tissue metabolism corresponds to functions of dhatvagni at various levels as below:
 
Rasa Dhatwagni: Glucose metabolism, circulation in portal vein, formation of WBC
Rasa Dhatwagni: Glucose metabolism, circulation in portal vein, formation of WBC
Raktadhatwagni:Hemopoeisis, iron metabolism, protein metabolism
Raktadhatwagni:Hemopoeisis, iron metabolism, protein metabolism
Mamsadhatwagni: Protein metabolism  
Mamsadhatwagni: Protein metabolism  
Medodhatwagni:Lipid metabolism  
Medodhatwagni:Lipid metabolism  
Asthidhatwagni: Calcium and phosphorous metabolism, thyroid & parathyroid control  
Asthidhatwagni: Calcium and phosphorous metabolism, thyroid & parathyroid control  
Majjadhatwagni:Protein metabolism, iron metabolism, hemopoietic and erythroclastic activity
Majjadhatwagni:Protein metabolism, iron metabolism, hemopoietic and erythroclastic activity
Sukradhatwagni: Glucose metabolism, protein metabolism, vitamin E metabolism
Sukradhatwagni: Glucose metabolism, protein metabolism, vitamin E metabolism
Stem cells and poshaka dhatu:  
 
In Ayurveda research field, the concept of rasayana with respect to dhatu and stem cells is initially introduced by Prasad BS .On the basis of stem cell type potency, this development is continued throughout life. It is found that the bone marrow contains at least two kinds of stem cells. One population, called hematopoietic stem cells, forms all types of blood cells in the body. A second small population called non-hematopoietic stem cell can generate bone, cartilage, fat and cells that support the formation of blood and fibrous connective tissue (skeletal stem cells). In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions. Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew. Rasa Dhatu may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.  Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency. Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation. Thus, each dhatu carry the potency to regenerate further dhatu, because each avayava (organ) is formed by composition of many dhatus.  
'''Stem cells and poshaka dhatu''':  
 
In Ayurveda research field, the concept of rasayana with respect to dhatu and stem cells is initially introduced by Prasad BS .On the basis of stem cell type potency, this development is continued throughout life. It is found that the bone marrow contains at least two kinds of stem cells. One population, called hematopoietic stem cells, forms all types of blood cells in the body. A second small population called non-hematopoietic stem cell can generate bone, cartilage, fat and cells that support the formation of blood and fibrous connective tissue (skeletal stem cells).  
 
In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions. Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew.  
 
Rasa Dhatu may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.   
 
Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency. Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation.  
 
Thus, each dhatu carry the potency to regenerate further dhatu, because each avayava (organ) is formed by composition of many dhatus.  
===List of thesis done===
===List of thesis done===
1. Upadhyay Vashudev J (2001) :Medo-Dhatvagni ka SthaulyaRogakeSandharbhameinSaidhantikaevamPrayogikaAdhyayana, Department of Basic principles, IPGT&RA,Jamnagar.
1. Upadhyay Vashudev J (2001) :Medo-Dhatvagni ka Sthaulya Roga ke Sandharbha mein Saidhantika evam Prayogika Adhyayana, Department of Basic principles, IPGT&RA,Jamnagar.
 
2.Kishor G Satani(2011) : An Applied Study of Interrelationship of Jatharagni and Dhatvagni in Context to Dhatuvrddhi, Department of Basic principles, IPGT&RA,Jamnagar.
2.Kishor G Satani(2011) : An Applied Study of Interrelationship of Jatharagni and Dhatvagni in Context to Dhatuvrddhi, Department of Basic principles, IPGT&RA,Jamnagar.