Apasmara Nidana: Difference between revisions

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Although the management of ''apasmara'' is described further in [[Chikitsa Sthana]], principles of management are given in this chapter. The curable types of epilepsy should be carefully treated with strong elimination and alleviation therapies according to the vitiated dosha. ''Doshas'' present in the vessels above the heart need to be removed which require strong measures requiring medicines having higher penetrability, higher potency and highest bio-availability. With this objective, ''tikshna samshodhana'' (strong elimination) and ''samshamana'' (alleviation therapies) are employed. When extrinsic causative factors are involved (''agantu apasmara''), then ''mantras'' etc., will be useful.

The rationale behind advocating strong elimination therapies is the deeper location and excess vitiated state of doshas. As described in patho-physiology earlier the dosha are in dormant state in the vessels above heart. Therefore to remove these dosha, strong eliminatory therapies are needed. The strength of the prescribed medicine is decided by their higher penetrability, potency and bio-availability.

Practical application of principles:

The rationale behind advocating strong elimination therapies is the deeper location and excess vitiated state of ''doshas''. As described in patho-physiology earlier the ''dosha'' are in dormant state in the vessels above heart. Therefore to remove these ''dosha'', strong eliminatory therapies are needed. The strength of the prescribed medicine is decided by their higher penetrability, potency and bio-availability.

All the abovementioned principles are practically applicable. The methods for further research include the following:

1. Supporting the clinical presentation with data of research papers on survey studies

==== Practical application of principles ====

2. Preparing Checklist & proforma for

A. Diagnosis of states susceptible for suffering from ~~Apasmara~~

All the abovementioned principles are practically applicable. The methods for further research include the following:

B. Diagnosis of aura stage or premonitory stage of ~~Apasmara~~ for early identification of status epilepticus in order to train the patient and arrange necessary preventive measures

3. Diagnosis of apasmara and specific types of apasmara based on clinical presentation

#Supporting the clinical presentation with data of research papers on survey studies

Research areas:

#Preparing Checklist and proforma for

1. Evaluation studies of various epigenetic pathways in conjunction with the patho-physiology of apasmara

##Diagnosis of states susceptible for suffering from ''apasmara''

2. Clinical correlation with modern radiological investigations like CT etc. and EEG for better clinical diagnosis of ~~Apasmara~~

##Diagnosis of aura stage or premonitory stage of ''apasmara'' for early identification of status epilepticus in order to train the patient and arrange necessary preventive measures

3. Enlisting newly introduced disease commonly observed in society into the umbrella of ~~Apasmara~~ e.g. Alzheimer’s dementia, depression etc.

#Diagnosis of ''apasmara'' and specific types of ''apasmara'' based on clinical presentation

4. Retrospective analyses of all signs and symptoms enlisted in the modern text books and formulating probable samprapti / pathophysiology (dosha-dushya sammurchchna) based on dosha dominance behind manifestation of each sign and symptom can be formulated for better understanding in Ayurvedic perspective.

5. Assessment criteria in Ayurveda and modern science, modern investigation methods and technologies, biomarkers which are well established may be enlisted.

=== Research areas ===

#Evaluation studies of various epigenetic pathways in conjunction with the patho-physiology of ''apasmara''

#Clinical correlation with modern radiological investigations like CT etc. and EEG for better clinical diagnosis of ''apasmara''

#Enlisting newly introduced disease commonly observed in society into the umbrella of ''apasmara'' e.g. Alzheimer’s dementia, depression etc.

#Retrospective analyses of all signs and symptoms enlisted in the modern text books and formulating probable ''samprapti'' / pathophysiology (''dosha-dushya sammurchchna'') based on ''dosha'' dominance behind manifestation of each sign and symptom can be formulated for better understanding in Ayurvedic perspective.

#Assessment criteria in [https://en.wikipedia.org/wiki/Ayurveda Ayurveda] and modern science, modern investigation methods and technologies, biomarkers which are well established may be enlisted.

=== Further reading ===

@@ Line 848: / Line 848: @@
 Although the management of ''apasmara'' is described further in [[Chikitsa Sthana]], principles of management are given in this chapter. The curable types of epilepsy should be carefully treated with strong elimination and alleviation therapies according to the vitiated dosha. ''Doshas'' present in the vessels above the heart need to be removed which require strong measures requiring medicines having higher penetrability, higher potency and highest bio-availability. With this objective, ''tikshna samshodhana'' (strong elimination) and ''samshamana'' (alleviation therapies) are employed. When extrinsic causative factors are involved (''agantu apasmara''), then ''mantras'' etc., will be useful.
-The rationale behind advocating strong elimination therapies is the deeper location and excess vitiated state of doshas. As described in patho-physiology earlier the dosha are in dormant state in the vessels above heart. Therefore to remove these dosha, strong eliminatory therapies are needed. The strength of the prescribed medicine is decided by their higher penetrability, potency and bio-availability.
-Practical application of principles:
+The rationale behind advocating strong elimination therapies is the deeper location and excess vitiated state of ''doshas''. As described in patho-physiology earlier the ''dosha'' are in dormant state in the vessels above heart. Therefore to remove these ''dosha'', strong eliminatory therapies are needed. The strength of the prescribed medicine is decided by their higher penetrability, potency and bio-availability.
-All the abovementioned principles are practically applicable. The methods for further research include the following:
-. Supporting the clinical presentation with data of research papers on survey studies
+==== Practical application of principles ====
-. Preparing Checklist & proforma for
-A. Diagnosis of states susceptible for suffering from Apasmara
+All the abovementioned principles are practically applicable. The methods for further research include the following:
-B. Diagnosis of aura stage or premonitory stage of Apasmara for early identification of status epilepticus in order to train the patient and arrange necessary preventive measures
-. Diagnosis of apasmara and specific types of apasmara based on clinical presentation
+#Supporting the clinical presentation with data of research papers on survey studies
-Research areas:
+#Preparing Checklist and  proforma for
-. Evaluation studies of various epigenetic pathways in conjunction with the patho-physiology of apasmara
+##Diagnosis of states susceptible for suffering from ''apasmara''
-. Clinical correlation with modern radiological investigations like CT etc. and EEG for better clinical diagnosis of Apasmara
+##Diagnosis of aura stage or premonitory stage of ''apasmara'' for early identification of status epilepticus in order to train the patient and arrange necessary preventive measures
-. Enlisting newly introduced disease commonly observed in society into the umbrella of Apasmara e.g. Alzheimer’s dementia, depression etc.
+#Diagnosis of ''apasmara'' and specific types of ''apasmara'' based on clinical presentation
-. Retrospective analyses of all signs and symptoms enlisted in the modern text books and formulating probable samprapti / pathophysiology (dosha-dushya sammurchchna) based on dosha dominance behind manifestation of each sign and symptom can be formulated for better understanding in Ayurvedic perspective.
-. Assessment criteria in Ayurveda and modern science, modern investigation methods and technologies, biomarkers which are well established may be enlisted.
+=== Research areas ===
+#Evaluation studies of various epigenetic pathways in conjunction with the patho-physiology of ''apasmara''
+#Clinical correlation with modern radiological investigations like CT etc. and EEG for better clinical diagnosis of ''apasmara''
+#Enlisting newly introduced disease commonly observed in society into the umbrella of ''apasmara'' e.g. Alzheimer’s dementia, depression etc.
+#Retrospective analyses of all signs and symptoms enlisted in the modern text books and formulating probable ''samprapti'' / pathophysiology (''dosha-dushya sammurchchna'') based on ''dosha'' dominance behind manifestation of each sign and symptom can be formulated for better understanding in Ayurvedic perspective.
+#Assessment criteria in [https://en.wikipedia.org/wiki/Ayurveda Ayurveda] and modern science, modern investigation methods and technologies, biomarkers which are well established may be enlisted.
 === Further reading ===