| After age 40 years, testosterone levels in men begin to decrease. This decline, alternatively referred to as the male climacteric, andropause, viropause, or partial androgen deficiency of the aging male (PADAM), may account for a number of pathophysiologic changes associated with aging. Decreased bone density, loss of lean body mass, depressed erythropoiesis, oligospermia, sexual dysfunction; cognitive deficits, memory problems, and depression have all been hypothesized to result from a reduction in serum androgen levels. The symptoms of andropause are indolent, because the nature of androgen loss with age is slow and progressive3. [179-180] | | After age 40 years, testosterone levels in men begin to decrease. This decline, alternatively referred to as the male climacteric, andropause, viropause, or partial androgen deficiency of the aging male (PADAM), may account for a number of pathophysiologic changes associated with aging. Decreased bone density, loss of lean body mass, depressed erythropoiesis, oligospermia, sexual dysfunction; cognitive deficits, memory problems, and depression have all been hypothesized to result from a reduction in serum androgen levels. The symptoms of andropause are indolent, because the nature of androgen loss with age is slow and progressive3. [179-180] |