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https://www.carakasamhitaonline.com/index.php?title=Naveganadharaniya_Adhyaya&oldid=41538. Accessed October 26, 2022. </ref> </p>
 
https://www.carakasamhitaonline.com/index.php?title=Naveganadharaniya_Adhyaya&oldid=41538. Accessed October 26, 2022. </ref> </p>
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== Karmaja vyadhi (diseases due to deeds in a previous life) ==
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<p style='text-align:justify;'>This is a group of diseases caused by the sinful acts of the previous life. The causative factors for this category of diseases are not at all traceable. The diseases caused by providence (actions of past life) will be relieved only after the effect of such actions, comes to an end (decay of karma).<ref name="ref41">Vagbhata. Sutra Sthana, Cha.12 Doshabhedeey Adhyaya verse 58-59. In: Harishastri Paradkar Vaidya, Editors. Ashtanga Hridayam. 1st ed. Varanasi: Krishnadas Academy;2000.p.204. </ref> The theory of natural destruction appropriately explains the rationale behind this concept.  </p>
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== Application in langhana chikitsa and upawasa (reduction therapies and fasting) ==
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<p style='text-align:justify;'>Fasting is one of the ten methods of langhana therapy.<ref name="ref42">Murthy K.N., Deole Y. S.. Langhanabrimhaniya Adhyaya verse18. In: Dwivedi R.B., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020.
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 https://www.carakasamhitaonline.com/mediawiki1.32.1/index.php?title=Langhanabrimhaniya_Adhyaya&oldid = 41152. Accessed October 26, 2022. </ref> Fasting includes complete abstinence from food. There is extensive empirical and observational evidence that medically supervised fasting is efficacious in treating many disorders. It prevents most chronic degenerative and chronic inflammatory diseases. Michalsen A. mentioned potential health-promoting effects of fasting like fasting-induced neuroendocrine activation and hermetic stress response, increased production of neurotrophic factors, reduced mitochondrial oxidative stress, general decrease of signals associated with aging, and promotion of autophagy.<ref name="ref43">Michalsen, A., & Li, C. (2013). Fasting therapy for treating and preventing disease - current state of evidence. Forschende Komplementarmedizin (2006), 20(6), 444–453. https://doi.org/10.1159/000357765 </ref><ref name="ref44">Wilhelmi de Toledo F, Buchinger A, Burggrabe H, et al. Fasting therapy - an expert panel update of the 2002 consensus guidelines. Forsch Komplementmed. 2013;20(6):434-443. doi:10.1159/000357602https://doi.org/10.1159/000357602 </ref> <br/>Fasting is a powerful approach to ignite digestion, which removes accumulated toxins in the body. Aam (metabolic toxins) is considered an underlying driver of all illnesses. Fasting destroys many metabolic toxins, removes the obstruction of the srotasa, and ignites the agni (digestive capacity). This process helps to combat illness.<ref name="ref45">Gaikwad S, Gaikwad P, Saxena V. Principles of Fasting in Ayurveda. International Journal of Science Environment and Technology (2017), 6 (1), 787-792 </ref> Fasting therapy works on the fundamentals of swabhavoparama vada. In the absence of cause (unwholesome food), the future manifestation of vishama dhatus is prohibited by abstaining from food intake. The destruction of previously formed aam and vishama dhatu takes place naturally.  </p>
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== Application in the cause of diseases ==
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<p style='text-align:justify;'>The effect of incompatible food is neutralized if taken in a small amount or occasionally.<ref name="ref46">Dubey S.D., Singh A.N., Singh A., Deole Y. S.. Atreyabhadrakapyiya Adhyaya ver.106. In: Sirdeshpande M.K., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020.
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 https://www.carakasamhitaonline.com/index.php?title=Atreyabhadrakapyiya_Adhyaya&oldid=41156. Accessed October 27, 2022. </ref> The equilibrium is disturbed, and diseases are formed only after regular exposure to unwholesome dravya. If unwholesome dravya are consumed occasionally or in very less amounts, it will not result in the manifestation of vishama dhatus. It stresses the importance of maintaining the continuum in manifesting the conditions viz. sama dhatu and vishama dhatu. Continuous practice plays a pivotal role.  <br/>The doctrine of causation (karya-karana siddhanta) has a vital role in the philosophical foundation. The cause-effect theory is accepted by all philosophical schools, including Ayurveda, with different viewpoints. But all stressed the importance of the material cause rather than (as is western philosophy) the efficient cause.<ref name="ref47">Apu Sutradhar. Causation in Indian Philosophy. IOSR Journal of Humanities And Social Science 2018 Sept; 23(9) Ver.3: 35-39. DOI: 10.9790/0837-2309033539.  https://www.iosrjournals.org/iosr-jhss/papers/Vol.%2023%20Issue9/Version-3/F2309033539.pdf . </ref>  This relationship is established despite other principal theories regarding the cause-and-effect relation. And hence for every manifestation, a specific cause is essential. The same is applicable to the continuation of human health. Dhatu vaishamya (disequilibrium state of dhatu) is an effect of exposure to vishama hetu (unwholesome regimens) and, conversely applies to sama dhatus. The things which manifest will undergo destruction due to their inherent nature. There is no need for a separate cause for their destruction. <br/>Swabhavoparama vada explains the importance of intervention and continuous practices of good diet and lifestyle to preserve health and manage diseases.  </p>
    
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