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== Current researches ==
== Current researches ==
=== Therapeutic exercise ===
=== Therapeutic exercise ===
<ul><li>Systematic regular exercise can improve cognitive function and memory. <ref name="ref10">Ptomey LT, Szabo AN, Willis EA, Gorczyca AM, Greene JL, Danon JC, et al. Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome. Disabil Heal J. 2019;11(3):486–90.</ref>.</li>
<ul style='text-align:justify;'><li>Systematic regular exercise can improve cognitive function and memory. <ref name="ref10">Ptomey LT, Szabo AN, Willis EA, Gorczyca AM, Greene JL, Danon JC, et al. Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome. Disabil Heal J. 2019;11(3):486–90.</ref>.</li>
<li>Exercise can be used as a tool for primary prevention in the past phase (before the onset), secondary prevention (in present cases) and prognosis of heart failure. <ref name="ref11">Cattadori G, Segurini C, Picozzi A, Padeletti L, Anzà C. Exercise and heart failure: an update. ESC Hear Fail. 2018;5(2):222–32.</ref>. </li>
<li>Exercise can be used as a tool for primary prevention in the past phase (before the onset), secondary prevention (in present cases) and prognosis of heart failure. <ref name="ref11">Cattadori G, Segurini C, Picozzi A, Padeletti L, Anzà C. Exercise and heart failure: an update. ESC Hear Fail. 2018;5(2):222–32.</ref>. </li>
<li>Regular aerobic exercise can decrease the depressive symptoms and thereby the pro-inflammatory IL6. <ref name="ref12">Ventura J, McEwen S, Subotnik K, Hellemann G, Ghadiali M, Rahimdel A, et al. Changes in inflammation are related to depression and amount of aerobic exercise in first episode schizophrenia. Early Interv Psychiatry. 2021;15(1):213–6.</ref>. </li>
<li>Regular aerobic exercise can decrease the depressive symptoms and thereby the pro-inflammatory IL6. <ref name="ref12">Ventura J, McEwen S, Subotnik K, Hellemann G, Ghadiali M, Rahimdel A, et al. Changes in inflammation are related to depression and amount of aerobic exercise in first episode schizophrenia. Early Interv Psychiatry. 2021;15(1):213–6.</ref>. </li>
<li>Aerobic exercise is the best tool for treating Parkinson's disease <ref name="ref18">Alberts JL, Rosenfeldt AB. The Universal Prescription for Parkinson’s Disease: Exercise. J Parkinsons Dis. 2020;10(s1):S21–7.</ref>. </li>
<li>Aerobic exercise is the best tool for treating Parkinson's disease <ref name="ref18">Alberts JL, Rosenfeldt AB. The Universal Prescription for Parkinson’s Disease: Exercise. J Parkinsons Dis. 2020;10(s1):S21–7.</ref>. </li>
<li>Physical exercise can be used as an alternative to antidepressants in older adults <ref name="ref19">López-Torres Hidalgo J, Aguilar Salmerón L, Boix Gras C, Campos Rosa M, Escobar Rabadán F, Escolano Vizcaíno C, et al. Effectiveness of physical exercise in the treatment of depression in older adults as an alternative to antidepressant drugs in primary care. BMC Psychiatry. 2019;19(1):1–7.</ref>.</li></ul>
<li>Physical exercise can be used as an alternative to antidepressants in older adults <ref name="ref19">López-Torres Hidalgo J, Aguilar Salmerón L, Boix Gras C, Campos Rosa M, Escobar Rabadán F, Escolano Vizcaíno C, et al. Effectiveness of physical exercise in the treatment of depression in older adults as an alternative to antidepressant drugs in primary care. BMC Psychiatry. 2019;19(1):1–7.</ref>.</li></ul>
=== Mental exertion ===
<ul style='text-align:justify;'><li>Mental exertion is a psychophysiological state caused by sustained and prolonged cognitive activity. The activities/ occupations that demand physical exertion will have a hampering influence by prior mental exertion. <ref name="ref6"/>.</li></ul>
=== Exercise diet ===
<ul style='text-align:justify;'><li>Plant protein can also enhance resting muscle protein synthesis (MPS). Plant protein containing essential amino acids especially leucine facilitates prolonged adaptations to exercise training similar to animal protein. <ref name="ref20"> Kerksick CM, Jagim A, Hagele A, Jäger R. Plant proteins and exercise: What role can plant proteins have in promoting adaptations to exercise? Nutrients. 2021;13(6):1–22. </ref>.</li></ul>
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