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→Purification of drugs
To reduce the toxicity (''vikasi guna'') of ''Danti'' and ''Dravanti'', Charaka evolved a process using ''Pippali'' and honey paste which is to be besmeared over the roots and once again to be smeared with mud and fomented with steam after drying up in sun. Chakrapani observes that heat of fire and sunrays makes the root free from adverse effects. This could be quoted as a best example of purification process employed for the removal of toxicity - a novel concept mentioned by Charaka. In the medieval ages, ''Rasashastra'' texts adopted several purificatory procedures for various herbal and metallic drugs.
To reduce the toxicity (''vikasi guna'') of ''Danti'' and ''Dravanti'', Charaka evolved a process using ''Pippali'' and honey paste which is to be besmeared over the roots and once again to be smeared with mud and fomented with steam after drying up in sun. Chakrapani observes that heat of fire and sunrays makes the root free from adverse effects. This could be quoted as a best example of purification process employed for the removal of toxicity - a novel concept mentioned by Charaka. In the medieval ages, ''Rasashastra'' texts adopted several purificatory procedures for various herbal and metallic drugs.
==== Sushruta's perspective of Kalpa sthana ====
The subject matter of Kalpasthana in Sushruta samhita is entirely different and deals with one of the Ashtangas of Ayurveda known as Damshtrachikitsa (Toxicology). Sushruta furnished the details of ''vamana'' and virechana drugs in Sutra sthana (43 and 44th chapter). Among vamana dravyas madanaphala, jimutaka pushpa, kutaja phala, ikshvaku pushpa, kritavedhana beeja and dhamargava phala are enumerated. Sushruta identified best virechaneeya drugs based on part used like, trivrit among root purgatives and amongst bark, fruits, oil, juice and latex, the drugs namely tilvaka, haritaki, erandataila (Castor oil), karavellaka and snuhi are considered as best respectively. Trivrit, danti, dravanti, tilvaka, haritaki, chaturangula, erandataila, snuhiksheera, saptala, and shankhini are enumerated under virechaneeya drugs. There is not much difference among the drugs enumerated in Charaka and Sushruta, but Sushruta included triphala, erandataila under virechana drugs
Charaka suggested root bark of tilvaka while Sushruta instructed to use bark of tilvaka. A purgative recipe is suggested for children, old people, delicate and patients suffering from dhatukshaya (weight loss/wasting condition) by Sushruta which includes erandataila (Castor oil) mixed with triphala kwatha and milk or meat soup. He also suggested chaturangula for children up to age 12. It appears that Sushruta suggested easily available purgatives.<ref>Sushruta samhita, Ed. By G. D. Shingal et al., Sutra Sthana 44/72-77.</ref>
=== Relevance of the concepts of [[Kalpa Sthana]] in the current clinical practices ===
=== Relevance of the concepts of [[Kalpa Sthana]] in the current clinical practices ===