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                                                                                         [Ma.Ni.22/42]<ref name=":2">Madhavakara. Madhava Nidanam (Roga vinischaya). Translated from Sanskrit by K. R. Srikantha Murthy. 8th ed. Varanasi: Chaukhambha orientalia;2007</ref>
 
                                                                                         [Ma.Ni.22/42]<ref name=":2">Madhavakara. Madhava Nidanam (Roga vinischaya). Translated from Sanskrit by K. R. Srikantha Murthy. 8th ed. Varanasi: Chaukhambha orientalia;2007</ref>
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===Pathogenesis===
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The vata dosha is aggravated due to two possible pathologies:
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1. Depletion of body constituents (dhatu kshaya)
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2. Obstruction or covering of vata dosha by other dosha or body constituents (dhatu, mala)
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These two causes provide a background for pathogenesis of vata dominant diseases.
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The aggravated vata is lodged in vacant spaces or afflicted channels (sroto vaigunya). Due to obstruction in its path or impaired movement, vata dosha affects the indriya (sensory and motor organs) and leads to affliction of either side of the body. It also causes the desiccation of siras (nerves) and snayus (tendons), producing contractions of legs and hands on either side. [Cha.Sa. Chikitsa Sthana 28/43-45]
      
==Pathogenesis==
 
==Pathogenesis==
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