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Exercise and fasting has a very positive effect on anabolic disorders. Exercise results in reduction in fasting blood glucose, which replicates previous beneficial effects of exercise interventions in type II diabetes.   
 
Exercise and fasting has a very positive effect on anabolic disorders. Exercise results in reduction in fasting blood glucose, which replicates previous beneficial effects of exercise interventions in type II diabetes.   
 
   
 
   
==== Fasting ====
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===== Fasting =====
    
That fasting and CR (calorie restriction) makes an organism’s metabolic process more efficient, enhancing the organism’s age, is a well-researched subject. Clive McCay at Cornell had published, in 1937, that a 33% caloric restriction resulted in a 50% increase in the maximum lifespan of a rat. Similar experiments were done on organisms such as yeasts, mosquitoes, flies, protozoa, roundworms, fish, etc. Many decades later, the National Institute of Aging (NIA) and the universities of Maryland and Wisconsin tried to study the impact of CR on aging using primates (squirrel and rhesus monkeys). The NIA Primate CR study indicated that CR monkeys “demonstrated an improved metabolic profile”, though they also concluded that the effects of CR in long-lived animals are complex and depend on a variety of factors besides caloric restriction.  
 
That fasting and CR (calorie restriction) makes an organism’s metabolic process more efficient, enhancing the organism’s age, is a well-researched subject. Clive McCay at Cornell had published, in 1937, that a 33% caloric restriction resulted in a 50% increase in the maximum lifespan of a rat. Similar experiments were done on organisms such as yeasts, mosquitoes, flies, protozoa, roundworms, fish, etc. Many decades later, the National Institute of Aging (NIA) and the universities of Maryland and Wisconsin tried to study the impact of CR on aging using primates (squirrel and rhesus monkeys). The NIA Primate CR study indicated that CR monkeys “demonstrated an improved metabolic profile”, though they also concluded that the effects of CR in long-lived animals are complex and depend on a variety of factors besides caloric restriction.  
Herbs used in management of santarpaniya diseases:
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While treating santarpanajanya vyadhis like sthulata (obesity) and madhumeha (diabetes), consumption of dravyas that have guru and ruksha properties is advised. Along with medicines, the diet must also be ruksha. For skin ailments, applying powders of medicinal plants all over the body which can provide relief from kandu (itching) and kotha (pre-gangrenous condition) are advised. So the food must be guru and apatarpaka, i.e., it should induce catabolic activities. Applying these powders on the lesions may improve blood circulation which may consequently improve the increased hydroxylysine and glucose disaccharide content, decrease in proteoglycan and heparin sulfate and decrease in lysine content towards the lesion. The effects of honey, a food rich in antioxidants, on diseases such as cancer, coronary diseases, inflammatory disorders, and aging, has helped it gain lot of attention among nutritionists.  Properties of honey are ruksha, guru, and kashaya. Food and medicine having these properties enhance akasha and vayu mahabhuta which tends the person towards apatarpana.  
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===== Herbs used in management of ''santarpaniya'' diseases =====
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While treating ''santarpanajanya vyadhis'' like ''sthulata'' (obesity) and ''madhumeha'' (diabetes), consumption of ''dravyas'' that have ''guru'' and ''ruksha'' properties is advised. Along with medicines, the diet must also be ''ruksha''. For skin ailments, applying powders of medicinal plants all over the body which can provide relief from ''kandu'' (itching) and ''kotha'' (pre-gangrenous condition) are advised. So the food must be ''guru'' and ''apatarpaka'', i.e., it should induce catabolic activities. Applying these powders on the lesions may improve blood circulation which may consequently improve the increased hydroxylysine and glucose disaccharide content, decrease in proteoglycan and heparin sulfate and decrease in lysine content towards the lesion. The effects of honey, a food rich in antioxidants, on diseases such as cancer, coronary diseases, inflammatory disorders, and aging, has helped it gain lot of attention among nutritionists.  Properties of honey are ''ruksha, guru,'' and ''kashaya''. Food and medicine having these properties enhance ''akasha'' and ''vayu mahabhuta'' which tends the person towards ''apatarpana''.  
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Since ruksha dravyas are akasha and vayu dominant, medicines and food articles of this property are advised. Of the three properties of honey, the most important one is guru. Since jatharagni is vitiated in obesity (since agni plays an important role in causing or aggravating anabolic disorders), guru and ruksha substances are used to pacify it, and thus honey is recommended for obesity. However, the use of honey in diabetes is controversial since honey is full of fructose and it imparts hyperglycaemic properties on diabetic patients. In diseases like obesity, lipid abnormality and diabetes mellitus, gut microbiota plays an important role in carbohydrate metabolism.  
 
Since ruksha dravyas are akasha and vayu dominant, medicines and food articles of this property are advised. Of the three properties of honey, the most important one is guru. Since jatharagni is vitiated in obesity (since agni plays an important role in causing or aggravating anabolic disorders), guru and ruksha substances are used to pacify it, and thus honey is recommended for obesity. However, the use of honey in diabetes is controversial since honey is full of fructose and it imparts hyperglycaemic properties on diabetic patients. In diseases like obesity, lipid abnormality and diabetes mellitus, gut microbiota plays an important role in carbohydrate metabolism.  
 
Pericarp of haritaki showed cardiotonic activities in frog hearts, increasing the force of contraction and cardiac output without altering the heart rate  . Haritaki extracts administered before initiating any treatment showed signs of reduced myocardial damage caused by isoproterenol in rats. Haritaki reduced lipid peroxidation and significantly reduced cholesterolemia, aortic sudanophilia, and cholesterol content of the aorta and liver.   
 
Pericarp of haritaki showed cardiotonic activities in frog hearts, increasing the force of contraction and cardiac output without altering the heart rate  . Haritaki extracts administered before initiating any treatment showed signs of reduced myocardial damage caused by isoproterenol in rats. Haritaki reduced lipid peroxidation and significantly reduced cholesterolemia, aortic sudanophilia, and cholesterol content of the aorta and liver.