Changes

== Update of Research carried out on Nitya Sevaniya and Asevaniya food ==

== Update of Research carried out on Nitya Sevaniya and Asevaniya food ==

<ol style="text-align:justify;"><li style="font-weight:bold">Experimental study of selected Nitya Sevaniya and Asevaniya food items:<ref name="ref106"></ref></li>

<ol style="text-align:justify;"><li style="font-weight:bold">Experimental study of selected Nitya Sevaniya and Asevaniya food items:<ref name="ref106">Saylee Deshmukh, Mahesh Vyas, Mukesh Kumar B. Nariya. An experimental study to evaluate the effect of Nitya Sevaniya (daily consumable) and Nitya Asevaniya (daily non-consumable) food items on albino rats. Ayu. 2019;40(4):247-255.</ref></li>

<b>Methodoogy:</b> <br/>The study was conducted for in vivo safety evaluation of selected Nitya Sevaniya and Nitya Asevaniya food items. Thirty rats were randomly divided into five groups-each containing six Charle's Foster strain albino rats. Group 1 served as standard diet group, groups 2 and 3 served as test drug received groups namely NS50 and NS100, in which 50% and 100% mixture of Nitya Sevaniya food was administered, respectively. Group 4 and 5 as test drug received groups Nitya Asevaniya 50 (NAS50) and Nitya Asevaniya 100 (NAS100), in which 50% and 100% Nitya Asevaniya food mixtures was administered, respectively. The test diet was administered orally in the form of freshly prepared pellet twice a day ad libitum for 90 days. Parameters studied were gross behavior, body and organ weight, food and water intake, fecal and urine output, hematological and biochemical parameters, electrocardiogram and histology of various organs. <br/><br/><b>Results:</b> <br/>In the NAS100 group, a significant change was observed in 20 of 47 parameters in view of pathological aspect. Among them, three parameters, i.e., platelet count, serum glutamic-oxaloacetic transaminase (SGOT) and indirect bilirubin were above normal limits, while other parameters were within the normal limits. No significant change was observed in any of the parameters in the NS50 and NS100 group after 90 days of administration as compared with the control group. Considering findings of this study, it is concluded that selected NS food items are safe while consumption of only selected Nitya Asevaniya food items (when administered in 100% dose) for 90 days have the potential of inflammatory changes in the liver, spleen; fat deposition in kidney and impairment of cardiac and renal functions.

<b>Methodoogy:</b> <br/>The study was conducted for in vivo safety evaluation of selected Nitya Sevaniya and Nitya Asevaniya food items. Thirty rats were randomly divided into five groups-each containing six Charle's Foster strain albino rats. Group 1 served as standard diet group, groups 2 and 3 served as test drug received groups namely NS50 and NS100, in which 50% and 100% mixture of Nitya Sevaniya food was administered, respectively. Group 4 and 5 as test drug received groups Nitya Asevaniya 50 (NAS50) and Nitya Asevaniya 100 (NAS100), in which 50% and 100% Nitya Asevaniya food mixtures was administered, respectively. The test diet was administered orally in the form of freshly prepared pellet twice a day ad libitum for 90 days. Parameters studied were gross behavior, body and organ weight, food and water intake, fecal and urine output, hematological and biochemical parameters, electrocardiogram and histology of various organs. <br/><br/><b>Results:</b> <br/>In the NAS100 group, a significant change was observed in 20 of 47 parameters in view of pathological aspect. Among them, three parameters, i.e., platelet count, serum glutamic-oxaloacetic transaminase (SGOT) and indirect bilirubin were above normal limits, while other parameters were within the normal limits. No significant change was observed in any of the parameters in the NS50 and NS100 group after 90 days of administration as compared with the control group. Considering findings of this study, it is concluded that selected NS food items are safe while consumption of only selected Nitya Asevaniya food items (when administered in 100% dose) for 90 days have the potential of inflammatory changes in the liver, spleen; fat deposition in kidney and impairment of cardiac and renal functions.

<li style="font-weight:bold"></li>

<li style="font-weight:bold">Evaluation of effect of Rocksalt (Saindhava lavana)<ref name="ref107">Acharya Megha, Shubhangi Kamble, Mukesh Nariya, Hitesh A. Vyas, A.S. Baghel. Thesis. An experimental study of Nityasevaniya w.s.r. to Saindhava Lavana. Institute of Post Graduate Teaching and Research in Ayurveda, 2018.</ref>:</li>

<li style="font-weight:bold"></li>

<b>Methodology:</b> <br/>This study was carried out to assess the effects of Saindhava Lavana (Rock salt) on general behavior and physiological parameters in albino rats at different doses. For control group, standard diet was provided throughout the study period. For Test diet group:  Saindhava Lavana (Raw sample of Rock salt) mixed with powder of pellet at TED and TED*2 dose. The Therapeutic dose for experimental study was calculated based on body surface ratio by referring to the table of Paget’s and Barnes. <br/><br/><b>Results:</b> <br/>Systolic and Mean Blood pressure is significantly increased. This is due to mridu-shlathana actions of saindhava; in spite of increase in blood pressure there is no any pathological change was found in heart or other organ in TED level. Significant increase in kidney weight may be because of high dietary sodium and further may be inflammation or other associated effects as observed in histo-pathological study of kidney. Elevated dietary sodium expands the extracellular volume and increases cardiac output and ultimately Blood Pressure. High salt diets were associated with a breakdown of muscle protein. Which is supported by increased s. globulin in this study. mild increase in Spermatogenesis in Testis in saindhava (TED) supports Vrishya (aphrodisiac) property; while there were mixed effects of normal cytoarchitecture, fatty changes, cell infiltration with significant weight increase of Kidney at TED*2 level. Saindhava lavana maintains normalcy of health but not in excess dose.</ol>

<li style="font-weight:bold"></li>

<li style="font-weight:bold"></li></ol>

 

<big>'''[[Special:ContactMe|Send us your suggestions and feedback on this page.]]'''</big>

<big>'''[[Special:ContactMe|Send us your suggestions and feedback on this page.]]'''</big>